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KMID : 0363219940320040735
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Korean Journal of Dermatology
1994 Volume.32 No. 4 p.735 ~ p.739
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A Case of Epidermolysis Bullosa Simplex(Dowling-Meara Type)
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Abstract
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The Dowling-Meara type of epidermolysis bullosa simplex(EBS) is a genetic disease that is transmitted as an autosomal dominant trait and is characterized clinically by herpetiform clustering of blisters and palmo-plantar keratoderma. The disease
usually
presents at birth or in early infancy. Although serious and hemorrhagic blisters may occur on any part of the body, the lesions heal without scarring in general. The disease shows a tendency to improve by progression of age and it usually follws
a
relatively benign course. Microscopically, there are intraepidermal blisters forming as a result of cytolysis of basal cells. In addition, there is a highly characteristic clumping of tonofilaments of keratinocytes in type of EBS that is first
described
in Korean medical literatures.
(Kor J Dermatol 1994 ; 32(4) : 735~739)
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